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Center for Bionanoscience Research (CIBION), National Scientific and Technical Research Council (CONICET)
Physics Department, Faculty of Exact and Natural Sciences, University of Buenos Aires (UBA)

 Using optical methods, we explore the properties and technological applications of nanoparticles, single molecules, nanostructured materials, supramolecular assemblies, biological and hybrid nanosystems.

The Applied nanoPhysics Group was launched in October 2009 at the Physics Department, Faculty of Exact and Natural Sciences,  of the University of Buenos Aires (UBA)

In 2012 we moved our labs to the Center for Bionanoscience Research (CIBION) of the National Scientific and Technical Research Council (CONICET), while Prof. Stefani still holds his position at the Physics Department of the University of Buenos Aires.

CURRENT RESEARCH ACTIVITIES

Fluorescence nanoscopy.

Super-resolution fluorescence microscopy, also known as fluorescence nanoscopy, has revolutionized biological imaging because they provide deep sub-wavelenght spatial resolution while keeping the low-invasiveness of far-field optical interrogation. We apply and optimize well-established methods like STED and STORM, and develop new ones, such as MINFLUX, and open-source software for fluorescence nanoscopy. With them, we address questions of cellular and neuronal biology.

Optical printing colloidal nanoparticles.

Colloidal chemistry enables the fabrication of nanoparticles of different shapes, sizes and material compositions, that exhibit unique physical and chemical properties, inexistent in bulk materials. In order to make use of those properties in devices and circuits, it is necessary to develope methods to bring the colloidal nanoparticles from the liquid phase to specific locations of solid substrates. We address this challenge using optical forces.

Self-assembled Nanophotonic Devices.

Semiconductor-based devices are approaching intrinsic limits of speed and heat dissipation.
Optical devices are faster and practically loss-less, but their size miniaturization is limited by the wavelength of light. Nanophotonics and Plasmonics deals with the manipulation of light at the nanoscale. We investigate light-matter interaction between single-photon emitters and metallic nanoparticles organized in nanodevices by self-assembly.

LATESTS NEWS

Manipulation of nanoscale heat dissipation to improve optical printing

September 17th, 2017|

Optical printing is a wonderful tool to fabricate arrays of colloidal nanoparticles on solid substrates. However, when a nanoparticle absorbs light, it heats up and generates very large temperature gradients. In turn, those temperature gradients produce thermo-phoretic and thermo-osmotic forces that are strong enough to disturb the optical manipulation of [...]

Precision and mechanistic details of optical

September 1st, 2017|

Optical printing is a wonderful tool to capture colloidal nanoparticles from suspension and place them on specific positions of a substrate. Still, the mechanistic details of the processes involved are complex and not fully understood. In our recent publication in ACS Nano, we provide new insight into the mechanism of [...]

Summer festival meeting with Prof. Hell

August 3rd, 2017|

During the summer festival of the Max-Planck-Institute for Biophysical Chemistry, we had the chance to discuss with Stefan about the impact and future development of MINFLUX. Thank you Stefan for the constant support!  

Georg Foster Research Award to Prof. Fernando Stefani

July 4th, 2017|

The Georg Forster Research Award is granted by the prestigious Alexander von Humboldt Foundation (AvH) in recognition of a researcher's entire achievements to date to academics of all disciplines whose fundamental discoveries, new theories, or insights have had a significant impact on their own discipline and beyond and who are expected [...]

DINAMO 2017 in Siglufjordur, Iceland

May 22nd, 2017|

The conference Discussions on Nano and Mesoscopic Optics (DINAMO) aims to promote the transfer of knowledge between different branches of optical sciences and to stimulate global solutions to complex questions nano- and mesosopic optics. DINAMO is conceived to provide an interdisciplinary forum where leading scientists from around the world could [...]

Congratulations Dr. Gargiulo!

March 23rd, 2017|

Today, Julian Gargiulo defended his doctoral thesis "Optical printing of metallic nanoparticles" at the Physics Department of the Faculty of Exact and Natural Sciences, University of Buenos Aires, obtaining the highest honors. Colloidal chemistry provides an enormous variety of nanoparticles, with different shapes, sizes and material composition. These nanomaterials have [...]

Congratulations Dr. Barabas!

March 23rd, 2017|

Today, Federico Barabas defended his doctoral thesis "Nanoscopía de fluorescencia por localización estocástica de moléculas individuales" at the Physics Department of the Faculty of Exact and Natural Sciences, University of Buenos Aires, obtaining the highest honors. We highly appreciate the evaluation by the jury: Prof. Dr. Francisco Barrantes, Prof. Dr. [...]

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THE GROUP

PROF. FERNANDO D. STEFANI
PROF. FERNANDO D. STEFANIPrincipal Investigator
DR. LUCÍA LÓPEZ
DR. LUCÍA LÓPEZStaff Researcher and Lab Manager
Dr. ALAN SZALAI
Dr. ALAN SZALAIAssistant Researcher
Super-resolution fluorescence microscpy, Single-molecule biophysics
DR. JULIÁN GARGIULO
DR. JULIÁN GARGIULOAssistant Researcher (INS-UNSAM, CIBION)
Optical printing colloidal nanoparticles. Plasmon-assisted chemistry.
FLORIAN HABERKORN WAIGEL
FLORIAN HABERKORN WAIGELPh.D. candidate in Physics (University of Buenos Aires)
Single-particle tracking with p-MINFLUX
FACUNDO ROUQUAUD
FACUNDO ROUQUAUDUndergraduate student in Physics (University of Buenos Aires)
pulsed-interleavead STED-FRET
GONZALO ESCALANTE
GONZALO ESCALANTEPh.D. candidate in Physics (University of Buenos Aires)
Super-resolution imaging of protein organization
FLORENCIA CHOQUE
FLORENCIA CHOQUEPh.D. candidate in Physics (University of Buenos Aires)
pulsed interleaved MINFLUX
FLORENCIA EDORNA
FLORENCIA EDORNAPh.D. candidate in Physics (University of Buenos Aires)
Single-molecule localization through sequential structured illumination
LOURDES SIMÓ
LOURDES SIMÓUndergraduate student in Physics (University of Buenos Aires)
3D super-resolution imaging
GROUP PICTURES

COLLABORATORS

STEFAN HELL
Max-Planck-Institute for Biophysical Chemistry (Göttingen, Germany)

THOMAS JOVIN
Max-Planck-Institute for Biophysical Chemistry (Göttingen, Germany)

ALFREDO CÁCERES
Instituto Universitario de Ciencias Biomédidas de Córdoba (Córdoba, Argentina)

PHILIP TINNEFELD
Ludwig-Maximilians-University Munich (Germany)

GUILLERMO ACUNA
University of Fribourg (Switzerland)

ANDRÉS ZELCER
Centro de Investigaciones en Bionanociencias (Buenos Aires, Argentina)

ANDREA BRAGAS
University of Buenos Aires (Argentina)

DARÍO KRAPF
Instituto de Biología Molecular y Celular de Rosario (IBR – Santa Fe, Argentina)

SABRINA SIMONCELLI
University College London (UK)

DAMIAN REFOJO
Biomedicine Research Institute of Buenos Aires (Argentina)

RODRIGO PALACIOS
Universidad Nacional de Río Cuarto (Córdoba, Argentina)

OSCAR CAMPETELLA
Universidad Nacional de General San Martín (Buenos Aires, Argentina)

SPONSORS

We highly appreciate the support by

CONTACT

Centro de Investigaciones en Bionanociencias (CIBION, CONICET)

Godoy Cruz 2390 – Piso 1

C1425FQD Buenos Aires, Argentina

T: +54 11 4899-5500 int. 5596

E: cibion@cibion.conicet.gov.ar

W: https://stefani-lab.ar/

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