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Center for Bionanoscience Research (CIBION), National Scientific and Technical Research Council (CONICET)
Physics Department, Faculty of Exact and Natural Sciences, University of Buenos Aires (UBA)

 Using optical methods, we explore the properties and technological applications of nanoparticles, single molecules, nanostructured materials, supramolecular assemblies, biological and hybrid nanosystems.

The Applied nanoPhysics Group was launched in October 2009 at the Physics Department, Faculty of Exact and Natural Sciences,  of the University of Buenos Aires (UBA)

In 2012 we moved our labs to the Center for Bionanoscience Research (CIBION) of the National Scientific and Technical Research Council (CONICET), while Prof. Stefani still holds his position at the Physics Department of the University of Buenos Aires.

CURRENT RESEARCH ACTIVITIES

Fluorescence nanoscopy.

Super-resolution fluorescence microscopy, also known as fluorescence nanoscopy, has revolutionized biological imaging because they provide deep sub-wavelenght spatial resolution while keeping the low-invasiveness of far-field optical interrogation. We apply and optimize well-established methods like STED and STORM, and develop new ones, such as MINFLUX, and open-source software for fluorescence nanoscopy. With them, we address questions of cellular and neuronal biology.

Optical printing colloidal nanoparticles.

Colloidal chemistry enables the fabrication of nanoparticles of different shapes, sizes and material compositions, that exhibit unique physical and chemical properties, inexistent in bulk materials. In order to make use of those properties in devices and circuits, it is necessary to develope methods to bring the colloidal nanoparticles from the liquid phase to specific locations of solid substrates. We address this challenge using optical forces.

Self-assembled Nanophotonic Devices.

Semiconductor-based devices are approaching intrinsic limits of speed and heat dissipation.
Optical devices are faster and practically loss-less, but their size miniaturization is limited by the wavelength of light. Nanophotonics and Plasmonics deals with the manipulation of light at the nanoscale. We investigate light-matter interaction between single-photon emitters and metallic nanoparticles organized in nanodevices by self-assembly.

LATESTS NEWS

Visiting Professor Marcelo Nollmann

October 30th, 2018|

We are glad to welcome Dr. Marcelo Nollmann from the Center for Structural Biochemistry in Montpellier (CNRS/INSERM) as visiting Professor at the Physics Department of the University of Buenos Aires   During his stay, Dr. Nollmann will give a course for graduate and undergraduate students of the Faculty of Exacts [...]

Dr. Mariano Barella visits Imperial College London

October 20th, 2018|

As part of our collaboration with the group of Prof. Stefan Maier, Dr. Mariano Barella travelled to London for a research stay at Imperial College. During his stay, Mariano will discuss and perform kick-off experiments for a new project with Dr. Julian Gargiulo, an ex-member of our lab currently working [...]

11ᵗʰ Advanced Scientific Programming in Python

September 5th, 2018|

Luciano Masullo participated in the 11ᵗʰ Advanced Scientific Programming in Python, taking place in Camerino, Italy, from 3rd to 8th of September The school focused on advanced Python programming for scientific application and was aimed at scientific investigators, not professional programmers. Among other topics, the participants learned strategies and methods [...]

8th Single Molecule Localization Microscopy Symposium

August 27th, 2018|

Cecilia Zaza and Luciano Masullo participated in the 8th Single Molecule Localization Microscopy Symposium, presenting the software Gollum for the automated quantification of periodic protein structures The meeting took place at the beautiful Harnack Haus of the Max-Planck Society in Berlin, Germany. More information about the symposium at https://2018.smlms.org/ More info [...]

Super-resolution imaging at the cell membrane of breast cancer cells

July 8th, 2018|

Estrogen receptor α (ERα) is expressed in tissues as diverse as brains and mammary glands. In breast cancer, ERα is a key regulator of tumor progression. Therefore, understanding what activates ERα is critical for cancer treatment in particular and cell biology in general.     In this interdisciplinary work, a [...]

1st Summer School on Photothermal Effects in Plasmonics

June 25th, 2018|

Dr. Ianina Violi and Cecilia Zaza obtained a travel grant to attend the 1st Summer School on Photothermal Effects in Plasmonics, taking place in Porquerolles’ Island, France, and they made the sacrifice to represent the group...   The school gathered more than 60 researchers from around the world, including our [...]

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THE GROUP

PROF. FERNANDO D. STEFANI
PROF. FERNANDO D. STEFANIPrincipal Investigator
DR. LUCÍA LÓPEZ
DR. LUCÍA LÓPEZStaff Researcher and Lab Manager
Dr. ALAN SZALAI
Dr. ALAN SZALAIAssistant Researcher
Super-resolution fluorescence microscpy, Single-molecule biophysics
DR. JULIÁN GARGIULO
DR. JULIÁN GARGIULOAssistant Researcher (INS-UNSAM, CIBION)
Optical printing colloidal nanoparticles. Plasmon-assisted chemistry.
FLORIAN HABERKORN WAIGEL
FLORIAN HABERKORN WAIGELPh.D. candidate in Physics (University of Buenos Aires)
Single-particle tracking with p-MINFLUX
FACUNDO ROUQUAUD
FACUNDO ROUQUAUDUndergraduate student in Physics (University of Buenos Aires)
pulsed-interleavead STED-FRET
GONZALO ESCALANTE
GONZALO ESCALANTEPh.D. candidate in Physics (University of Buenos Aires)
Super-resolution imaging of protein organization
FLORENCIA CHOQUE
FLORENCIA CHOQUEPh.D. candidate in Physics (University of Buenos Aires)
pulsed interleaved MINFLUX
FLORENCIA EDORNA
FLORENCIA EDORNAPh.D. candidate in Physics (University of Buenos Aires)
Single-molecule localization through sequential structured illumination
LOURDES SIMÓ
LOURDES SIMÓUndergraduate student in Physics (University of Buenos Aires)
3D super-resolution imaging
GROUP PICTURES

COLLABORATORS

STEFAN HELL
Max-Planck-Institute for Biophysical Chemistry (Göttingen, Germany)

THOMAS JOVIN
Max-Planck-Institute for Biophysical Chemistry (Göttingen, Germany)

ALFREDO CÁCERES
Instituto Universitario de Ciencias Biomédidas de Córdoba (Córdoba, Argentina)

PHILIP TINNEFELD
Ludwig-Maximilians-University Munich (Germany)

GUILLERMO ACUNA
University of Fribourg (Switzerland)

ANDRÉS ZELCER
Centro de Investigaciones en Bionanociencias (Buenos Aires, Argentina)

ANDREA BRAGAS
University of Buenos Aires (Argentina)

DARÍO KRAPF
Instituto de Biología Molecular y Celular de Rosario (IBR – Santa Fe, Argentina)

SABRINA SIMONCELLI
University College London (UK)

DAMIAN REFOJO
Biomedicine Research Institute of Buenos Aires (Argentina)

RODRIGO PALACIOS
Universidad Nacional de Río Cuarto (Córdoba, Argentina)

OSCAR CAMPETELLA
Universidad Nacional de General San Martín (Buenos Aires, Argentina)

SPONSORS

We highly appreciate the support by

CONTACT

Centro de Investigaciones en Bionanociencias (CIBION, CONICET)

Godoy Cruz 2390 – Piso 1

C1425FQD Buenos Aires, Argentina

T: +54 11 4899-5500 int. 5596

E: cibion@cibion.conicet.gov.ar

W: https://stefani-lab.ar/

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