Center for Bionanoscience Research (CIBION), National Scientific and Technical Research Council (CONICET)
Physics Department, Faculty of Exact and Natural Sciences, University of Buenos Aires (UBA)
Using optical methods, we explore the properties and technological applications of nanoparticles, single molecules, nanostructured materials, supramolecular assemblies, biological and hybrid nanosystems.
The Applied nanoPhysics Group was launched in October 2009 at the Physics Department, Faculty of Exact and Natural Sciences, of the University of Buenos Aires (UBA)
In 2012 we moved our labs to the Center for Bionanoscience Research (CIBION) of the National Scientific and Technical Research Council (CONICET), while Prof. Stefani still holds his position at the Physics Department of the University of Buenos Aires.
CURRENT RESEARCH ACTIVITIES
Fluorescence nanoscopy.
Super-resolution fluorescence microscopy, also known as fluorescence nanoscopy, has revolutionized biological imaging because they provide deep sub-wavelenght spatial resolution while keeping the low-invasiveness of far-field optical interrogation. We apply and optimize well-established methods like STED and STORM, and develop new ones, such as MINFLUX, and open-source software for fluorescence nanoscopy. With them, we address questions of cellular and neuronal biology.
Optical printing colloidal nanoparticles.
Colloidal chemistry enables the fabrication of nanoparticles of different shapes, sizes and material compositions, that exhibit unique physical and chemical properties, inexistent in bulk materials. In order to make use of those properties in devices and circuits, it is necessary to develope methods to bring the colloidal nanoparticles from the liquid phase to specific locations of solid substrates. We address this challenge using optical forces.
Self-assembled Nanophotonic Devices.
Semiconductor-based devices are approaching intrinsic limits of speed and heat dissipation.
Optical devices are faster and practically loss-less, but their size miniaturization is limited by the wavelength of light. Nanophotonics and Plasmonics deals with the manipulation of light at the nanoscale. We investigate light-matter interaction between single-photon emitters and metallic nanoparticles organized in nanodevices by self-assembly.
LATESTS NEWS
Congratulations Dr. Bordenave!
Today, Martin Diego Bordenave defended his PhD thesis "Mediciones con resolución nanométrica mediante depleción por emisión estimulada" at the Physics Department of the Faculty of Exact and Natural Sciences, University of Buenos Aires, obtaining the highest honors. In his thesis, Martín built and applied two STED nanoscopes: - firstly, [...]
Presupuesto MINCYT, ANPCYT, CONICET, CONAE
Es importante que la comunidad científica, y sus socios industriales, conozcan la evolución de la inversión pública en el sistema científico. Lamentablemente, el proyecto de ley de presupuesto enviado por el Poder Ejecutivo Nacional impone importantes recortes para el año próximo. Los invito a leer, comentar y ampliar estos estudio: [...]
Directional, light-induced growth of nanoparticles
Although there are numerous ways reported to induce the growth of nanoparticles with light, very little is known about the role of polarization. Most of the experiments reported so far were done with nanoparticles in suspension, where only average information can be obtained and the role of the polarization of [...]
STED at the emission maximum
In order to obtain super-resolved images, STED nanoscopy uses a laser tuned at the red tail of the emission spectrum of the fluorophore to deplete the excited state by stimulated emission. Since the stimulated emission cross-section follows practically the same dependency with wavelength as the emission, this configuration involves very [...]
Visit to production plant and R&D department of Wiener Lab
We visited the production plant and R&D department of Wiener-lab in Rosario (Santa Fé, Argentina), as part of a series of meetings where we are evaluating a collaboration to develop a new platform for homogeneous biosensing. In the picture: Catalina von Bilderling (CIBION), Gustavo Capriotti (Wiener), Fernando D. Stefani [...]
OSA Student Chapter – 1st Meeting Young Researchers in Optics and Photophysics of Argentina
CIBION hosted the first meeting of Young Researchers in Optics and Photophysics of Argentina sponsored by the Optical Society of America (OSA) through its Student Chapter. It was a day full of enthusiastic and interesting talks and discussions. Thank you Cecilia Zaza for the local organization.
Meeting with our neurobiology collaborators
Today, we spent all day discussing and brain-storming with our collaborators from the groups of Dr. Damián Refojo (IBIOBA-CONICET, Buenos Aires) and Dr. Alfredo Cáceres (INIMEC-CONICET, Córdoba) We discussed the advances made in our collaborative projects and planned new experiments. In the picture: Raquel Becerra (Ph.D. candidate, Refojo´s group), Catalina [...]
Connecting metallic nanoparticles by optical printing
Using optical forces it is possible to "print" colloidal metallic nanoparticles on specific locations of a substrate, directly from the suspension. In this way, it is possible to fabricate arrays of nanoparticles of arbitrary geometry. See for example the map of Argentina made of individual gold nanoparticles of 60 nm [...]
COLLABORATORS
STEFAN HELL
Max-Planck-Institute for Biophysical Chemistry (Göttingen, Germany)
THOMAS JOVIN
Max-Planck-Institute for Biophysical Chemistry (Göttingen, Germany)
ALFREDO CÁCERES
Instituto Universitario de Ciencias Biomédidas de Córdoba (Córdoba, Argentina)
PHILIP TINNEFELD
Ludwig-Maximilians-University Munich (Germany)
GUILLERMO ACUNA
University of Fribourg (Switzerland)
ANDRÉS ZELCER
Centro de Investigaciones en Bionanociencias (Buenos Aires, Argentina)
ANDREA BRAGAS
University of Buenos Aires (Argentina)
DARÍO KRAPF
Instituto de Biología Molecular y Celular de Rosario (IBR – Santa Fe, Argentina)
SABRINA SIMONCELLI
University College London (UK)
DAMIAN REFOJO
Biomedicine Research Institute of Buenos Aires (Argentina)
RODRIGO PALACIOS
Universidad Nacional de Río Cuarto (Córdoba, Argentina)
OSCAR CAMPETELLA
Universidad Nacional de General San Martín (Buenos Aires, Argentina)

















